张盛 肿瘤内科,副主任医师
1996-1997年在日本国立爱媛大学医学院附属医院留学,2004-2006于加拿大MCMASTER大学肿瘤中心留学。先后在山东淄博市中心医院、青岛医学院附属医院、上海交通大学附属第一人民医院等医院工作。2008.12晋升副主任医师及上海交通大学肿瘤学硕士生导师。2010.8调复旦大学附属肿瘤医院工作。曾获2005年山东省科技进步三等奖,2006年加拿大CIHR研究奖,2008年上海市浦江人才等。第一作者发表SCI收录论文9篇
主要学术成绩:
o 2002年获国际实验血液学会(ISEH) INTERNATIONAL TRAVEL GRANT 专项奖励 (该年度中国地区两名获奖人之一)
o 2005-2006 年度获加拿大国立卫生研究院(CIHR)研究奖
o 2005年度山东省科技进步三等奖(第一位)。项目名称:树突状细胞联合细胞因子激活的T细胞抗白血病和肿瘤的实验研究。编号:JB2005-3-64-1
发表论文(均为第一作者及通信作者,均为SCI收录)
1. Zhang S(张盛), Wang Q, Li WF, Wang HY, Zhang HJ. Enhanced antitumor immunity by murine cytokine activated T lymphocytes after cocultured with bone marrow derived dendritic cells pulsed with whole tumor lysates. Leuk Res 2004;28:1085-8(IF 3.0)
2. Zhang S(张盛), Zhang HJ, Wang HY, Wang Q, Li WF, Yu L. CD4+ T cells tumor specific response exists in L615 leukemia mice: adoptive transfer in combination with cyclophosphamide. Exp Oncol 2004;26:156-7(IF 1.5)
3. Zhang S(张盛), Wang Q, Li WF, Wang HY, Zhang HJ, Zhu JJ. Different antitumor immunity roles of cytokine activated T lymphocytes from naive murine splenocytes and from dendritic cells-based vaccine primed splenocytes: implications for adoptive immunotherapy. Exp Oncol 2004;26:55-62(IF 1.5)
4. Zhang S(张盛), Li WF, Zhang HJ, Wang Q. Antitumor reactivity of splenocytes primed in vivo with dendritic-cell-based vaccine and secondarily activated with a cocktail of cytokines in vitro. Exp Oncol 2004;26:243-5(IF 1.5)
5.Zhang S(张盛), Wang Q, Miao B. dendritic cell-based vaccine in the treatment of patients with advanced melanoma. Cancer Biother Radiopharm. 2007;22:501-7(IF 2.0)
6.Zhang S, Wang Q.Factors determining the formation and release of bioactive IL-12: regulatory mechanisms for IL-12p70 synthesis and inhibition. Biochem Biophys Res Commun. 2008;372:509-12(IF 3.0)
7.Zhang S(张盛). and Huang W. Dendritic cell based genetic immunization stimulates potent tumor protection dependent on CD8 CTL cells in the absence of autoimmunity. J Cancer Res Clin Oncol. 2008. 134:987-94(IF 2.9)
8. Zhang S(张盛), Bernard D, Khan WI, Kaplan MH, Bramson JL, Wan Y. CD4+ T-cell-mediated anti-tumor immunity can be uncoupled from autoimmunity via the STAT4/STAT6 signaling axis. Eur J Immunol. 2009. 39:1252-9(IF 5.3)
9. Zhang S(张盛), Zhang HJ and Zhao JD. Biochem Biophys Res Commun. The role of CD4 T cell help for CD8 CTL activation. 2009. 384: 405-8(IF 3.0)